ECE1508F 2005: Topics in Computational Molecular Biology

Project proposals due Oct 19 (note revised due date!)

Instructor: Brendan J. Frey
Associate Professor
Electrical and Computer Engineering
University of Toronto
Contact information

Information sheet for this course

Link to NCBI version of Human Molecular Genetics 2

List of potential papers (assigned papers at top):

Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs. Brendan Frey, Sep 14/19, 2005.
Listening to silence and understanding nonsense: Exonic mutations that affect splicing. Ofer Shai, Sep 21/26, 2005.
Review of non-coding RNAs. Functions of microRNAs. Jim Huang, Sep 28, 2005.
Sequence alignment, with insertions, deletions, etc. Inmar Givoni, Oct 3, 2005.
Cell-based DNA cloning. PCR, DNA sequencing, and in vitro mutagenesis. Isaac Li, Oct 5, 2005.
Class cancelled, Oct 12, 2005.
Microarray technologies. Eddie Ng, Oct 17, 2005.
Microarray technologies. Eddie Ng, Oct 19, 2005.
Mass spectrometry. Clement Chung, Oct 24, 2005.
Mass spectrometry. Clement Chung, Oct 26, 2005.
Predicting gene functions. Quaid Morris, Oct 31, 2005.
Predicting gene functions. Quaid Morris, Nov 2, 2005.
Single Nucleotide Polymorphisms (SNPs). Abida Raouf, Nov 7, 2005.
Single Nucleotide Polymorphisms (SNPs). Abida Raouf, Nov 9, 2005.
Non-coding RNA and RNA secondary (2-D) structure. Sarah Ali, Nov 14, 2005.
Gene finding methods based on DNA sequence. Nov 21, 2005.
Human immune response. Emad Shenouda, Nov 23, 2005.
The transcriptional landscape of the mammalian genome.
RNA structure: Reading the ribosome.
Reporter assays.
Transcriptional regulation.
Protein-protein interaction networks.